Drug Response

How to Choose the Best Antidepressant

Antidepressant use in psychiatry: Nowadays, physicians have an arsenal of drugs to combat psychiatric disorders: Anxiolytics, Antidepressants, Anti-psychotics, and Mood stabilizers. However, as with most other drugs, one dosage does NOT apply to all patients. A certain amount of drug might offer desired clinical improvements to some while under the same regiment others may exhibit [...]

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Detrol (Tolterodine) Side Effects Include Sleep Disturbance in Some Patients

Detrol (tolterodine) causes sleep disturbance side effects in patients who are slow drug metabolizers One of the most common manifestations of ‘urinary incontinence’ is excessive bladder wall contraction – causing an uncontrollable urge to visit the washroom. Antimuscarinics are the class of drugs given to patients suffering from urinary incontinence, and [...]

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Antidepressants: Understanding and Mitigating the Risks of Side Effects

Antidepressants: Understanding and Mitigating the Risks of Side Effects

A universal truth of all medications is that no matter how beneficial they may be, they are always associated with some risks. Perhaps some of the most controversial medications are antidepressants, especially when they are used to treat relatively mild or moderate depression since they can cause serious side [...]

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Colon cancer treatment and genetic testing for DPYD deficiency

Patients diagnosed with advanced colon cancer have few treatment options besides surgery and aggressive chemotherapy. All chemotherapies are designed to block cell growth. Since all multiplying cells need to replicate their DNA, blocking DNA synthesis stops cell growth. The 5-Fluorouracil (5FU) drug is a modified nucleotide that blocks DNA [...]

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