Drug Response

I have stars in my genome! Or how genetic variations affect your drug response

How drugs affect the body Many commonly used drugs can be helpful for most while causing adverse reactions in others. Medication needs to be absorbed and then metabolized into a biologically active form or inactivated at a certain rate. Drug absorption and secretion (i.e. pharmacokinetics) can be affected by certain [...]

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cardiovascular

Statin adverse side effects vs risk of stroke and heart attack: how to balance the risks?

Statins have long being used for reducing the risk of heart attack and stroke in patients at high risk of cardiovascular disease, particularly in obese and Type 2 Diabetes patients. Clinical trials have demonstrated the positive role of statins in risk reduction that extended well beyond the associated reduction [...]

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personal genetics

Genetic susceptibility to smoking

Decision to Smoke The future look into potential genetic treatment to quit smoking and some interesting HR policies Smokers have been broadly criticized for polluting the air around them with second hand smoke and now seeds of discussion are being planted around the implications of hiring smokers. But where does one’s desire [...]

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pharmacogenetics

Are you Tylenol or Advil person? Alleviating pain through genetics

Chronic pain is not only debilitating and horrible consequence of chronic diseases, trauma, but is also inevitable consequence of medical treatments. Chronic pain is refractory to most of the treatments, but we believe that genetics of pain and pharmacogenetics can substantially improve pain management. In many cases chronic pain arises [...]

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cholesterol

Is lean steak healthy?

Is lean steak – high in protein, low in fat & cholesterol – heart healthy? The answer surprising … Intuition would elude one to believe lean steak to be a healthier red meat option especially when it comes to maintaining top notch cardiac functions. With specs of high protein, low [...]

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Data and Healthcare

Companies all over the world leverage big data to assess the health of their organization and measure the impact of tools or technologies they use to deliver the products or services. From a business stand point effective interpretation of these metrics saves time and money devoted to seeking the [...]

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genome sequencing

Should I pay or should I go? Or what do we really know about mutations and disease liability?

Current genome sequencing technologies already allow for cost effective and comprehensive disease prediction. However, for the average consumer, does it really make sense to pay $5,000 for a whole genome analysis at this time? And what can they gain from an analysis of this sort? After all, genome sequencing [...]

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