Why Pillcheck?
The most common challenge with prescription drugs is unwelcome side effects. And sometimes, they are simply not effective for the individual. Pillcheck is a fast, easy DNA test that helps identify the right medication at the right dosage from a broad spectrum of drugs. Share your results with your doctor, who can help you get on the right medications, so you feel better, sooner.
78% of prescriptions were changed with insights from Pillcheck test results!†
Rated 4.6/5 stars on dnatestingchoice.com
It was reassuring to know that my son has a low risk of side effects to his prescription and so he was willing to give it a try. It’s been several months now and he is feeling so much better.
Feedback on Pillcheck has been very positive and the service has helped my patients make the right decisions on their prescriptions.
It has changed the way my illness is treated and has helped me immensely!
Very quick results, easy instructions and valuable information.
Pillcheck stopped years of suffering from anxiety and depression with a DNA drug response test

Here is what you get with Pillcheck
- A personalized report that predicts drug response to all medications covered by the test.
- Your results reviewed by a specially trained pharmacist from a national network of pharmacogenetic practitioners.
- Results for a lifetime. Since your DNA doesn't change, your Pillcheck is valid for life and we update your report for new medications as guidelines expand.
Check your own prescriptions here
We analyze your DNA against all of the most commonly prescribed medications.
Pillcheck Protects Your Privacy
Pillcheck promises to keep your personal and genetic information confidential. Here’s what we do:
- Destroy your genetic sample after your report is complete
- Ensure your genetic data is not linked to your personal information in our system
- Allow you to decide who you share your results with
- Follow Canadian, U.S., and international health information privacy and security guidelines

HIPAA
COMPLIANT

PIPEDA
COMPLIANT

GDPR
COMPLIANT
How Much Does Pillcheck Cost?
The Pillcheck Service Includes:
- An advanced drug response test covering the most popular prescriptions
- Your personalized results report, good for your lifetime
- A pharmacist’s review and action plan to share with your doctor
- Free updates to your report for new medication information
- Free shipping within Canada

Order online
A DNA sample collection kit is sent to you.

Submit sample
Swab saliva from your cheek and send it back in the pre-paid envelope.

Access results
Your confidential results will be available online 1-2 weeks from when we receive your sample.

Share results
Take your results to your doctor to adjust your medications.
You should share your Pillcheck results with your doctor to consider when making treatment decisions to help you get on medication that is most likely to be safe and effective based on your DNA.
Some doctors may be unfamiliar with Pharmacogenetics or have questions about our service. If your doctor has questions, here's a helpful information sheet you can pass along (a printed copy is included in the sample kit). They can also contact Pillcheck directly by phone at 1-877-409-3629 Monday to Friday, 9AM-5PM EST or by email at service@pillcheck.ca.
Individuals have full ownership and control over their Pillcheck test results. Personal data is not shared without prior authorization as described in the Informed Consent Form. Only the individual can decide who has access to the report and can revoke access at any time or request deletion of the information by submitting a request in writing at service@pillcheck.ca.
Privacy of genetic and personal data is protected by the Bill S201 (an Act to prohibit and prevent genetic discrimination) and Personal Information Protection and Electronic Documents Act (PIPEDA). The Pillcheck service is fully compliant with these Acts. Except as expressly set forth in the participant’s Informed Consent, results are not shared with any third party, including insurance company and employer.
For more details, please refer to our Privacy Policy and Consent Form.
Pillcheck uses genetic markers optimized for enhanced sensitivity for accurate results in ethnically diverse populations, regardless of gender.
We test for genetic variations in the liver enzymes CYP2C9, CYP2C19, CYP2B6, CYP2D6, CYP2C8, CYP1A2, CYP3A4, CYP3A5 and other enzymes affecting drug metabolism, transport or response, including ABCG2, NAT2, G6PD, UGT1A1, UGT2B15, TPMT, NUDT15, DPYD, ADRB2, OPRM1, SLCO1B1, F2, F5, and VKORC1.
Pillcheck analyzes only the specific genes involved in drug metabolism and does not assess your risk for disease.
Pharmacogenetic testing, like Pillcheck, can predict your response and risk of side effects based on your drug metabolism. It can help rule out metabolism issues, but it is not an allergy test and does not assess immune response. This blog provides more information on the difference between drug allergy and drug intolerance. Please consult your doctor or pharmacist if you suspect you may have a drug allergy.
Health benefits and insurance companies may cover the cost of the Pillcheck service as an optional benefit. Pillcheck results do not impact coverage decisions.
Pillcheck does NOT assess any genes related to disease risk or disease diagnostics and does not affect patients’ insurance. Only specific, well-identified DNA variations related to drug response are analyzed by Pillcheck. Once the test is complete, any remaining DNA is destroyed after 30 days.
For more details, please refer to our Privacy Policy and Consent Form.
Only specific, well-identified DNA variations related to drug response are analyzed by the lab. This is analyzed, and the results are used to generate a personalized report listing your body’s predicted response to all Pillcheck-covered medications. Once the test is complete, any remaining DNA is destroyed after 30 days.
Get on the right medications.
† Journal of the American Pharmacists Association 2017 Sep-Oct;57(5):624-629