Personalized mental health treatment through genetic insights
Find your path to better mental health
The journey to effective mental health treatment shouldn't be a maze of trial and error.
Pillcheck pharmacogenetic testing provides personalized insights that can help your healthcare provider select medications that work better with your unique genetic profile—potentially reducing side effects and improving outcomes.
Why mental health medication matches matter
People with anxiety and depression recovered 10 weeks sooner when their medications were optimized using Pillcheck.
Mental health medications affect everyone differently. What works well for one person may cause side effects or prove ineffective for another. The difference often lies in your DNA.
Reduce the guesswork in finding effective medication
Minimize unwanted side effects that can discourage treatment
Identify medications that may work better with your genetic makeup
Avoid potential drug interactions with other medications you're taking
Covered mental health medications
Pillcheck analyzes how your body processes many commonly prescribed medications. These are just some of the common health concerns Pillcheck helps with.
ADHD
- Stimulants (Adderall, Vyvanse)
- SNRI antidepressants indicated for ADHD (Strattera, Wellbutrin, Qelbree)
- Blood pressure medication used for ADHD (guanfacine – Tenex and Intuniv)
Depression
- Antidepressants increasing serotonin levels (SSRIs: Prozac, Zoloft, Lexapro, Celexa)
- Antidepressants increasing norepinephrine and serotonin (SNRIs: Effexor, Cymbalta)
- Antidepressants increasing norepinephrine and dopamine (NDRIs: Wellbutrin)
- Atypical antidepressants (Trintellix, Remeron, Viibryd)
- Tricyclic antidepressants (Anafranil, Elavil, Silenor, Tofranil)
Anxiety
- Benzodiazepines (Ativan, Serax, Valium, Xanax, KlonoPIN)
- Non-benzodiazepine antianxiety drugs (Buspar, Valdoxan, Defanyl, Desyrel)
- Blood pressure medications (Beta-blockers: Lopresor, Betaloc, Propral, Ranoprin)
Sleep disorders (insomnia)
- Sleep-stimulating drugs (Hypnotics: Lunesta, Halcion, Imovane, Zimovane)
- Wakefulness-promoting medications (modafinil, Wakix)
Other mental health disorders
- Mood stabilizers (Depakene, Depakote)
- Atypical antipsychotics (Abilify, Latuda, Saphris, Seroquel, Rexulti, Zyprexa)
- Conventional antipsychotics (Trilafon)
Therapy recommendations for you and your doctor
Evidence-based genetic prescribing recommendations
Your medication history, demographics and lifestyle
Expert Pharmacist Review makes evidence relevant for the individual
Pillcheck's "whole person" approach incorporates the individual's medication experiences, DNA-based guidelines, and clinical pharmacists' expertise.
Real patients' experiences
With Pillcheck, you don't have to worry about choosing a treatment area. Pillcheck covers a broad range of medications in every test, making it useful now – and in the future.
Helped me finally find an anxiety med that works
5.0
October 21, 2024
I started taking the recommended medication and it gave me significant improvements in my mental health. Best SSRI I've tried and I've tried most of them
5.0
October 14, 2024
4 simple steps to a lifetime of the right medications
Order online
A DNA sample collection kit is sent to you.
Submit sample
Swab your cheek and mail sample back in the prepaid envelope. Fill out your Medical Profile online.
Access results
Your confidential results will be available online 1-2 weeks from when we receive your sample.
Share results
Take your results to your doctor to adjust your medications.
For healthcare providers
Pillcheck provides evidence-based, actionable insights to help optimize medication selection and dosing for your patients with mental health conditions.
- Guideline-based recommendations from clinical pharmacists
- Clear, easy-to-interpret reports
- Helps identify potential medication interactions
- Supports complex cases with multiple conditions
- May improve patient adherence and outcomes
Privacy & security
Testing only analyzes genes related to medication response
Follows PIPEDA privacy regulations
Your sample is destroyed after testing
Your data will never be sold or shared with third parties
Insurance coverage
Check your eligibility through your benefits administrator
No additional costs for future report updates
Lifetime value as your DNA profile never changes
Take the first step toward better mental health
$599
CAD + tax
after $__AMOUNT__ discount-
An advanced drug response test covering the most popular prescriptions
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Your personalized results report — good for your lifetime
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A pharmacist’s review and recommendations to share with your doctor
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Updates to your report for new medication guidelines
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Free shipping within Canada
Our team is here to help
It's important to share your Pillcheck results with your doctor to consider when making treatment decisions to help you get on medication that is most likely to be safe and effective based on your DNA.
Some doctors may be unfamiliar with Pharmacogenetics or have questions about our service. If your doctor has questions, here's a helpful information sheet you can pass along (a printed copy is included in the sample kit). They can also contact Pillcheck directly by phone at 1-877-409-3629 Monday to Friday, 9AM-5PM EST or by email at [email protected].
Pillcheck promises to keep your personal and genetic information confidential.
- Your sample is processed in Canada, and all data is securely stored in Canada.
- Once the test is complete, your DNA sample is destroyed within 30 days.
- Your genetic data is stored separately from your personal information in our encrypted systems.
- You decide who you share your results with.
- No personal health and genetic information will be shared with your employer, insurer, or any third party without your consent.
- Our test is not designed to assess disease risk, diagnosis, or ancestry.
- We follow Canadian, U.S., and international health information privacy and security guidelines.
For more details, please refer to our Privacy Policy and Consent Form.
Pillcheck reports more than 350 commonly prescribed medications in several treatment areas, including cardiac and gastrointestinal conditions, mental health, pain management and oncology.
View the complete list of covered medications.
Genetic testing for medications treating these conditions is recommended by the U.S. Food and Drug Administration (FDA), European Medicines Agency (EMA), Health Canada, Clinical Pharmacogenetics Implementation Consortium (CPIC), and the Dutch Pharmacogenetics Working Group (DPWG).
Pillcheck uses genetic markers optimized for enhanced sensitivity for accurate results in ethnically diverse populations, regardless of gender.
We test for genetic variations in the liver enzymes CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, CYP4F2 and other enzymes affecting drug metabolism, transport or response, including ABCG2, ADRB2, DPYD, F2, F5, G6PD, NAT2, NUDT15, OPRM1, SLCO1B1, TPMT, UGT1A1, UGT2B15, and VKORC1.
Pillcheck analyzes only the specific genes involved in drug metabolism and does not assess ancestry, your risk for disease, or provide disease diagnosis.
Pharmacogenetic testing, like Pillcheck, can predict your response and risk of side effects based on your drug metabolism. It can help rule out metabolism issues, but it is not an allergy test and does not assess immune response. This blog provides more information on the difference between drug allergy and drug intolerance. Please consult your doctor or pharmacist if you suspect you may have a drug allergy.
Your personal health and genetic information will be kept confidential and will never be shared with your employer, insurer, or any third party without your consent. Additionally, it is illegal under the Genetic Non-discrimination Act to use genetic information for insurance underwriting or employment. Therefore, Pillcheck results do not impact a person’s insurance or employment.
For more details, please refer to our Privacy Policy and Consent Form.
The lab analyzes the sample, and the results are used to generate a personalized report listing your body’s predicted response to all Pillcheck-covered medications. Only specific, well-identified DNA variations related to drug response are analyzed. Once the test is complete, any remaining DNA is destroyed after 30 days.
Pillcheck is a pharmacogenetic test intended to provide information to help your healthcare provider with medication decisions. It is not meant to diagnose or treat any condition. Always consult with your healthcare provider before making any changes to your medication regimen.