Discover your unique response to medications
Unlock what matters most with genetics
Helping you & your doctor find the best medications, so you feel better sooner.
Pillcheck – the right choice
Your medications tailored to your DNA
Genetic testing for medications helps you find the best treatment options and minimize your risk of side effects.
Expert pharmacist review
A Pillcheck pharmacist reviews your medications and writes a summary letter for your doctor with treatment options based on current symptoms and DNA.
Personalized insights for life
You get lifetime access to your drug response information, updated yearly for new medications and guidelines.
Is Pillcheck for me?
With Pillcheck, you don’t have to worry about choosing a treatment area. We cover a broad range of medications in every test, making it useful now — and in the future. These are just some of the common health concerns Pillcheck helps with:
Find the right mental health drug for you – Pillcheck is proven to help patients recover faster, with insights on over 70 of the most-prescribed mental health drugs for:
- Depression
- Anxiety
- ADHD (list of medications)
- Sleep disorders
- Addiction/substance abuse
Pillcheck helps you and your doctor find the right mental health medications for you. An independent Randomized Controlled Trial (RCT) confirmed that people struggling with depression and anxiety recovered faster with the Pillcheck service.
Painkillers can be highly effective at blunting severe pain. However, even the most frequently used pain medications may fail to provide adequate pain relief for some people.
Whether you are managing pain from injury, arthritis, migraines, fibromyalgia, or other chronic pain conditions, Pillcheck offers valuable insights into your body's response to various pain medications, helping you and your doctor make safer decisions when choosing pain therapy.
You can also reference your Pillcheck results before painful procedures, such as surgery, to determine the most effective treatment to support your recovery.
Feel better sooner with the peace of mind that you’re on the right medications and dosages, especially if you’re taking painkillers long-term.
The Pillcheck report includes predicted response to medications for:
- High cholesterol
- High blood pressure
- Arrhythmia
- Blood clots
- Congestive heart failure
Many people take multiple medications to manage one or more of these conditions, increasing the likelihood that one drug isn’t working as intended, as well as leaving them at risk for a cardiac event.
Taking the right medications reduces your risk of heart attack, stroke, and avoidable side effects like muscle pain and bleeding.
Pillcheck’s pharmacists and DNA analysis guide your doctor in prescribing the right drug and dosage based on your unique genetic makeup.
Up to one in four people get no relief from the most common acid reflux and digestive system drugs, and many are at risk of serious side effects, like infection and fractures, due to their genetic drug metabolism.
The Pillcheck report includes predicted response to medications to help manage symptoms of:
- IBD (ulcerative colitis, Crohn’s disease)
- IBS
- Acid reflux (GERD)
- Esophagitis
Pillcheck helps you and your doctor find the right drug and dosage for you. You can feel better sooner, avoid side effects, and improve the long-term safety of your treatment.
It's important to consider the age and hormonal activity of females when it comes to prescription medication.
Pregnancy, hormonal contraceptives, and hormone replacement therapies can alter drug metabolism.
When you take multiple medications or supplements, the likelihood of side effects or ineffective treatment increases. Fortunately, Pillcheck is a tool that can assist your doctor in understanding how your body metabolizes various medications, reducing the risk of rare but serious complications.
Why Pillcheck?
In an independent study, 78% of prescriptions were changed with insight from Pillcheck results.
Pillcheck, validated through independent clinical research, is the top choice for people with depression and anxiety wanting to feel better sooner.
4 simple steps to a lifetime of the right medications
Order online
A DNA sample collection kit is sent to you.
Submit sample
Swab your cheek and mail sample back in the prepaid envelope. Fill out your Medical Profile online.
Access results
Your confidential results will be available online 1-2 weeks from when we receive your sample.
Share results
Take your results to your doctor to adjust your medications.
How much does Pillcheck cost?
$599
CAD + tax
after $__AMOUNT__ discount-
An advanced drug response test covering the most popular prescriptions
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Your personalized results report — good for your lifetime
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A pharmacist’s review and recommendations to share with your doctor
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Updates to your report for new medication guidelines
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Free shipping within Canada
Frequently asked questions
It's important to share your Pillcheck results with your doctor to consider when making treatment decisions to help you get on medication that is most likely to be safe and effective based on your DNA.
Some doctors may be unfamiliar with Pharmacogenetics or have questions about our service. If your doctor has questions, here's a helpful information sheet you can pass along (a printed copy is included in the sample kit). They can also contact Pillcheck directly by phone at 1-877-409-3629 Monday to Friday, 9AM-5PM EST or by email at [email protected].
Pillcheck promises to keep your personal and genetic information confidential.
- Your sample is processed in Canada, and all data is securely stored in Canada.
- Once the test is complete, your DNA sample is destroyed within 30 days.
- Your genetic data is stored separately from your personal information in our encrypted systems.
- You decide who you share your results with.
- No personal health and genetic information will be shared with your employer, insurer, or any third party without your consent.
- Our test is not designed to assess disease risk, diagnosis, or ancestry.
- We follow Canadian, U.S., and international health information privacy and security guidelines.
For more details, please refer to our Privacy Policy and Consent Form.
Pillcheck reports more than 350 commonly prescribed medications in several treatment areas, including cardiac and gastrointestinal conditions, mental health, pain management and oncology.
View the complete list of covered medications.
Genetic testing for medications treating these conditions is recommended by the U.S. Food and Drug Administration (FDA), European Medicines Agency (EMA), Health Canada, Clinical Pharmacogenetics Implementation Consortium (CPIC), and the Dutch Pharmacogenetics Working Group (DPWG).
Pillcheck uses genetic markers optimized for enhanced sensitivity for accurate results in ethnically diverse populations, regardless of gender.
We test for genetic variations in the liver enzymes CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, CYP4F2 and other enzymes affecting drug metabolism, transport or response, including ABCG2, ADRB2, DPYD, F2, F5, G6PD, NAT2, NUDT15, OPRM1, SLCO1B1, TPMT, UGT1A1, UGT2B15, and VKORC1.
Pillcheck analyzes only the specific genes involved in drug metabolism and does not assess ancestry, your risk for disease, or provide disease diagnosis.
Pharmacogenetic testing, like Pillcheck, can predict your response and risk of side effects based on your drug metabolism. It can help rule out metabolism issues, but it is not an allergy test and does not assess immune response. This blog provides more information on the difference between drug allergy and drug intolerance. Please consult your doctor or pharmacist if you suspect you may have a drug allergy.
Your personal health and genetic information will be kept confidential and will never be shared with your employer, insurer, or any third party without your consent. Additionally, it is illegal under the Genetic Non-discrimination Act to use genetic information for insurance underwriting or employment. Therefore, Pillcheck results do not impact a person’s insurance or employment.
For more details, please refer to our Privacy Policy and Consent Form.
The lab analyzes the sample, and the results are used to generate a personalized report listing your body’s predicted response to all Pillcheck-covered medications. Only specific, well-identified DNA variations related to drug response are analyzed. Once the test is complete, any remaining DNA is destroyed after 30 days.