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Encountering Pharmacogenomic Test Results in Psychiatry

Precision medicine, using pharmacogenomic testing, can streamline the process of finding the right treatment for each patient’s depression and result in better outcomes. Pharmacogenomics, also called pharmacogenetics or PGx, facilitates a personalized prescribing approach that utilizes a person’s genetic information to inform medication selection and dosing decisions. While some...

Bupropion (Wellbutrin) as an alternative medication for SSRI intolerance

Bupropion (Wellbutrin) is a “second generation” antidepressant that differs from SSRIs. Bupropion acts as a norepinephrine–dopamine reuptake inhibitor and has a much lower involvement of the serotonin pathway. Therefore, bupropion is frequently used for people who did not respond to or could not tolerate SSRIs. In addition to depression...

Leveraging PGx to raise your value proposition in group benefits

If you’ve seen the movie Wall Street, you’ll remember the part when Charlie Sheen confronts the gregarious Wall Street money machine Gordon Gekko (Michael Douglas). Douglas glares at Sheen and says, “OK, pal, tell me something I don’t already know!” Timeless. Let’s talk about pharmacogenetic (PGx) testing, a form...

Precision medicine: a pragmatic addition to your DEI strategy

A recent study found that nearly 75% of employees in underrepresented groups — women, racial and ethnic minorities, and LGBTQ employees — do not feel they've personally benefited from their companies' diversity, equity and inclusion (DEI) programs. As many executives re-examined their organizations' diversity and inclusion initiatives, they discovered a reinvention...

Medication or therapy? What’s the best way to treat depression

Untreated depression can affect all facets of life. It can ruin relationships at work and home, disrupt sleep, increase the chance of risky behaviours such as drug or alcohol addiction, make it difficult to overcome physical illnesses. Appropriate treatment, however, can help most people with depression. Most people do best with depression...

How accurate is pharmacogenetic testing?

Pharmacogenetics uses a patient's genetic profile to accurately predict a drug's efficacy, guide dosage and improve the safety of treatments. Depending on your genetic makeup, some medications may work faster or slower, or produce more or fewer side effects. The scientific field of pharmacogenetics, the link between your unique...

Worried about side effects of arthritis medications? Your DNA is the key to long-term safety of treatment

People with arthritis take medications to manage pain and stem disease progression. However, long-term use of these drugs poses risks of severe complications including tuberculosis, increased risk of leukemia, heart disease and bleeding. Here we describe how the science of pharmacogenetics can help to improve the safety of treatment...

Personalized medicine: Improved mental health treatment guided by DNA

A growing body of evidence indicates that personalized medicine, or treatment guided by your DNA, improves mental health outcomes. A recent randomized clinical trial confirms that Pillcheck pharmacogenetics-guided medication therapy accelerates recovery for patients with depression and anxiety. Finding the right depression treatment is often challenging Only 30% of people suffering...

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