Comparison of antidepressants effectiveness and side effects – pharmacogenetics to assist in therapy selection

Patients suffering from depression, anxiety, post-traumatic stress disorder (PTSD) and other mental health conditions are frequently facing significant antidepressant side effects and often have a hard time finding the right dose or drug. When the medication is ineffective or the side effects become intolerable, patients have to switch to...

What is the difference between a drug allergy and drug intolerance?

All medications have the potential to cause side effects such as nausea, dizziness, stomach upset, rashes, and other issues. Pills contain ingredients which are supposed to improve a medication’s taste, color, absorption, or shelf life. Some of these chemicals are allergenic and can cause allergic reactions. Active ingredients of...

What alternative anxiety medication can be used if you cannot tolerate an SSRI?

Generalized anxiety disorder (GAD) is generally treated with Selective Serotonin Reuptake Inhibitors (SSRIs). First line SSRIs for GAD treatment include citalopram, escitalopram and sertraline. Clinical trials show response rates of 50% to 60%, remission rates between 25% and 35% and a significant proportion of patients who experience significant SSRI...

New treatments for treatment resistant depression: exercise, healthy diet, and ketamine.

Major depressive disorder, or MDD, affects 10-15% of people over their lifetime. The current standard of care includes cognitive behavioral therapy and several classes of medications, mainly Selective Serotonin Reuptake Inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). The combination of cognitive behavioral therapy and medical...

Supplements for depression and anxiety: Are they safe and effective?

Many people are concerned about the safety of antidepressants and are looking for natural alternatives. Although there are several natural products such as St. John’s Wort, S-adenosyl methionine (SAM-e), Rhodiola rosea, and omega-3 which have been shown to have mood stabilizing effects, supplements cannot substitute medications for people with...

Which antidepressants will work best for your post partum depression?

Becoming a mother is a time of immense happiness for most women. But new mothers also experience frustration, worry, disappointment and guilt. Postpartum “baby blues” are common and typically start days after birth and last up to two weeks. Symptoms include mood swings, anxiety, tearfulness, and trouble sleeping. Sometimes...