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Pain and depression drugs not working? Antidepressants can interfere with opioids

Pharmacists have been long aware of the risks of combining certain pain and depression drugs. Many common antidepressants can significantly reduce the pain relief of opioid painkillers. A recent large-scale study of people who were taking antidepressants and received opioids after surgery had higher pain scores as much as...

TECTA: use of proton pump inhibitors can increase the risk of COVID-19 infection

Updated November 2020 A recent study  pre-published by the American Journal of Gastroenterology has identified a connection between the use of Proton Pump Inhibitors (PPIs) and the risk of COVID-19 infections. The risk of contracting the infection appears to increase with the PPI dose. Here we describe how a pharmacogenetic test can...

Precision medicine of menopause and depression: treating hot flashes with antidepressants

Many women experience unpleasant symptoms leading up to, during, and after menopause. It is not uncommon to have hot flashes, insomnia and depression. Hot flashes can cause substantial physical and psychological discomfort. There are medical treatments available for women experiencing severe symptoms, including hormone therapy, antidepressants, and even antiepileptic...

Pillcheck PGx launches new program for benefits advisors on the heels of positive study results in the mental health area

The new program builds on the successful introduction of Pillcheck pharmacogenetics by many insurers seeking to impact the frequency and duration of Short-Term and Long-Term disability claims. Now the same rigorously evaluated, secure service is available to plans and benefit advisors on a subscription basis or as a private...

Reduced thyroid function and depression: a personalized medicine approach

Reduced thyroid function or hypothyroidism frequently develops unnoticed until more severe symptoms manifest themselves. It is estimated that 12% of the population in North America have abnormal thyroid function, and 60% of these individuals are unaware they have the condition. It’s a complex condition that can be caused by...

New Pillcheck Study in Long Term Care shows the potential benefit of matching people’s drug treatment to their DNA in Elder Care

Study shows that over 80% could benefit from a pharmacogenetic test and improve treatment. Many older adults, especially those in elder care, are at risk of harmful medication-related side effects. Often, the issues are preventable with an easy pharmacogenetic test and a medication review by an expert pharmacist. A recent study involving...

COVID-19 Complications: Optimizing medications for recovery using pharmacogenetics (PGx)

Over 10% of people infected with the SARS-CoV-2 virus experience acute respiratory distress syndrome (ARDS) and require supportive treatment with oxygen and even mechanical lung ventilation. Multiple COVID-19 complications occur because SARS family coronaviruses can cause extensive heart and lung damage. SARS-CoV-2 viruses can easily penetrate deep into these...

Can’t tolerate tamoxifen side effects, can I stop taking it? Pharmacogenetic testing improves treatment

Have you been prescribed hormone therapy for cancer but can’t tolerate tamoxifen side effects? For many women, tamoxifen side effects are too much to stomach, and the prospect of enduring them for five years is not appealing even at the risk of cancer recurrence. Tamoxifen is an option for hormone therapy...

Medication for endometriosis and uterine fibroids: Elagolix and other treatments

Elagolix is a new option for treating endometriosis and uterine fibroids Endometriosis and uterine fibroids are common conditions affecting women most often during their reproductive years. Both conditions can cause severe cramps, abdominal and lower back pain, as well as heavy or abnormal menstrual bleeding. Treatment options include pain relievers,...

Blood pressure medication and coronavirus: Do ACE2 blockers increase the risk of COVID-19?

Analysis of COVID-19 infections has identified that older patients with pre-existing conditions are at higher risk of severe disease. Doctors treating patients further emphasize that people with hypertension and heart disease are at higher risk of complications. This article discusses the relationship between blood pressure medication and coronavirus and...

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