Articles

Nearly half of dementia cases could be prevented or delayed. Learn how your genes affect statins, blood pressure medications and antidepressants, and why getting these medications right in midlife protects long-term brain health.

For most people, Reactine is the better everyday allergy medication. Learn how Benadryl and Reactine differ, how your CYP2D6 genes change their effect, which drug combinations to avoid, and why daily use of older antihistamines is linked to...

Many companies now sell genetic tests for GLP-1 drugs such as Ozempic, Wegovy and Mounjaro. Here is what variants in GLP1R, GIPR and ARRB1 can and cannot tell you about weight loss, nausea and serious side effects.

Mental health disability claims are the leading cost driver for Canadian plan sponsors. Learn how Pillcheck pharmacogenomic testing, pharmacist review and case manager workflows help shorten claims, with evidence from a Canadian randomized controlled trial.

Dizziness, fainting or palpitations on a medication can signal an abnormal heart rhythm. Learn what QT prolongation is, how genes such as CYP2D6 and CYP2C19 affect the risk with certain drugs, and what to do next.

Had a bad reaction to anesthesia, or have a relative who did? Learn how genes such as RYR1, CACNA1S and BCHE affect anesthesia safety, the red flags that suggest genetic testing before surgery, and your options.

It's not just DNA that affects drug response. Learn how sex, age and hormones change drug metabolism in women, and how pregnancy, hormonal contraceptives and menopause hormone therapy can change the way medications work.

Hot flashes, poor sleep and low mood often come together in menopause. Learn about hormone therapy, antidepressants, gabapentin and the new non-hormonal drugs, and how genes such as CYP2D6, CYP2C19 and F5 affect safety.

Finding the right treatment for depression often means trying several drugs. Learn the risks of trial and error, how CYP2D6 and CYP2C19 testing improves treatment, how PGx guidelines are expanding, and how insurance coverage is growing.

Many medications slow the gut and cause constipation. Learn which drugs are most often responsible, how supplements, vitamins and coffee can help or make it worse, and how genes and a medication review can help.

Psoriasis is a chronic autoimmune skin condition linked to higher heart risk and unhealthy blood lipids. Learn what research shows about statins and other cholesterol-lowering medications in psoriasis, and how SLCO1B1, ABCG2 and CYP2C9 testing helps choose a...

Sexual side effects such as low desire, trouble reaching orgasm and erection problems are common with many antidepressants and a frequent reason people stop treatment. Learn which antidepressants have fewer sexual side effects, what can help if they...

Can your genes affect fertility treatment? Learn how ovarian stimulation options compare, what CYP2D6 means for clomiphene, why letrozole has no genetic guidance, and how Factor V Leiden and prothrombin results help assess blood clot risk during IVF...

Wondering how to get a pharmacogenetic test in Canada? Learn what PGx testing is, where to order one, what it costs, whether your benefits plan covers it and how to choose a service you can trust.

Birth control pills slightly raise the risk of blood clots, and the risk is much higher with the Factor V Leiden or prothrombin G20210A gene variants. Learn how a simple genetic test helps you choose safer contraception.

Hormonal birth control is very effective, but it has been linked to depression, and methods that contain estrogen can cause blood clots. Learn what research shows, how Factor V Leiden and the F2 variant raise clot risk, which...

Stopping an antidepressant can cause withdrawal symptoms such as dizziness, irritability and flu-like feelings. Learn which antidepressants are harder to stop, how slow and hyperbolic tapering helps, and how your drug metabolism matters.

Endometriosis is hard to diagnose and is linked to hormones, inflammation and mental health. Learn about treatment options, from hormonal therapy and pain relievers to lifestyle changes, and how pharmacogenetic testing can guide safer medication choices.

Severe drug reactions such as Stevens-Johnson syndrome and DRESS are rare but dangerous. Learn how they differ from allergies, which genes such as HLA-B, G6PD and CYP2C9 raise the risk, and how the responsible drug is identified.

Bipolar disorder is often treated with lithium, other mood stabilizers and antipsychotics. Learn which medications work best, why antidepressants alone can be risky, and how pharmacogenetic testing helps choose safer, better-tolerated options.