Articles

Aspirin intolerance: role of your DNA

Aspirin is the most commonly used countertop drug to reduce pain, fever, and inflammation. It is also used to treat or prevent heart attacks and chest pain. But Aspirin is not suited to everyone. Many develop allergies to...
March 23, 2020 By Manoja Eswara

When Green Tea is NOT a Healthy Choice

Green tea extract, a readily available “natural health product” (NHP), can have a devastating impact on liver function in people who are deficient in certain key enzymes, leading to toxicity, liver injury, liver failure and even death. The...
March 23, 2020 By Antonietta Cerroni

New treatments for treatment resistant depression: exercise, healthy diet, and ketamine.

Major depressive disorder, or MDD, affects 10-15% of people over their lifetime. The current standard of care includes cognitive behavioral therapy and several classes of medications, mainly Selective Serotonin Reuptake Inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic...
March 23, 2020 By Ruslan Dorfman

Precision medicine and sleep medications

Many people have difficulty falling asleep, but for those suffering from anxiety, PTSD, depression, or chronic pain, insomnia is a major problem that contributes to worsening of symptoms. Your body’s circadian rhythm, exposure to blue light from electronic...
March 23, 2020 By Ruslan Dorfman

Choosing the best antidepressants for teenagers and seniors

Depression can affect both the young and old. Younger age group studies of depression show stress and social pressures from peers and parents alike can cause depression. However, rates of depression increase with age. Work-related stress, unsuccessful marriages,...
March 23, 2020 By Ruslan Dorfman

The SLC6A4 gene and response to antidepressants: Why the evidence still isn’t enough

Growing scientific evidence shows a link between the SLC6A4 gene and response to antidepressants. The SLC6A4 gene is involved in regulating serotonin – the brain chemical that influences everything from sleep to appetite to mood. Some genetic testing...
March 23, 2020 By Ruslan Dorfman

The Pillcheck Difference

Choosing the Right PGx Test As pharmacogenetics testing becomes more widely available, it is important to understand that not all tests are the same. Different testing companies provide different recommendations with regards to applying information from PGx tests...
March 23, 2020 By Ruslan Dorfman

Medical Liability in Pharmacogenetics - Risk vs. Benefit

The risk of side effects and adverse reactions is a constant threat when physicians prescribe medication. Pharmacogenetics (PGx) tries to mitigate that risk. Traditional prescribing takes age, weight, sex, and biochemical test results when available into account. Pharmacogenetics...
March 23, 2020 By Ruslan Dorfman

Quel est le meilleur médicament contre l'anxiété et la dépression?

Il est estimé que 17% des Nord-Américains connaîtront une grave dépression au cours de leur vie et 20% d’entre eux auront un trouble anxieux. Les antidépresseurs sont généralement prescrits pour soulager six grandes catégories de troubles anxieux et...
March 20, 2020 By Veronika Litinski

La kétamine, une option à considérer pour la dépression résistante au traitement conventionnel?

Chaque année des millions de personnes reçoivent un diagnostic de trouble dépressif majeur. Pour environ 30% de ces personnes, les antidépresseurs standards ne sont pas efficaces. Les personnes qui souffrent de dépression résistante au traitement épuisent généralement toutes...
March 20, 2020 By Ruslan Dorfman

How to find best genetic test for medications?

We all have been there: trying to make a best decision about something really complicated, like paying hundreds of $ for a medical test not covered by the health insurance. Genetic testing for mental health medications is in...
March 20, 2020 By Veronika Litinski

Est-ce que l'ibuprofène et le célécoxib peuvent aider à traiter ma dépression?

Nous pensons généralement que la dépression est causée par des déséquilibres chimiques dans le cerveau. Les molécules chimiques impliquées dans les mécanismes du cerveau - tels que la sérotonine et la noradrénaline - altèrent notre humeur et peuvent...
March 20, 2020 By Ruslan Dorfman

Managing expectations with pharmacogenetic testing

Pharmacogenetics is the science of how genes affect your body’s response to medications. Enzymes in the liver metabolize drugs so they can be cleared from the body. These enzymes are coded by genes, and variations in these genes...
March 20, 2020 By Ruslan Dorfman

Is the secret to reversing aging in our genes?

The search to reverse aging and extend lifespan has intrigued humanity ever since we developed awareness of our own mortality. New scientific data now suggests that the fountain of youth is in our genes. Researchers at the Salk...
March 20, 2020 By Ruslan Dorfman

How to Discuss Pharmacogenetics with Your Patients

Please click the following link to view this article pharmacytimes.com
March 20, 2020 By Ruslan Dorfman

Marijuana Addiction & Your Genes

In this current age of marijuana decriminalization, both in Canada and the United States, you often hear conflicting claims purporting the addictiveness – or lack thereof – of marijuana. In our contemporary era of hyper-polarized debates, where do...
March 19, 2020 By Ruslan Dorfman

How your genes can lower the chances of Carvedilol side effects

Carvedilol is a common prescription given to help lower blood pressure. However, determining whether carvedilol is the right medication for you, at what dose, and whether it will cause adverse side effects can be a long, drawn-out process...
March 19, 2020 By Ruslan Dorfman

What to do when Antidepressants Are Not Working

It can be quite challenging when antidepressants are not working. But, the treatment of depression remains one of trial-and-error. When a patient with clinical depression is prescribed an antidepressant, it takes about 4 to 6 weeks to find...
March 19, 2020 By Gouri Mukerjee

Data and Healthcare

Companies all over the world leverage big data to assess the health of their organization and measure the impact of tools or technologies they use to deliver the products or services. From a business stand point effective interpretation...
March 19, 2020 By Ruslan Dorfman